反应详情

The title compound was prepared from 2-chloro-4-methyl-6-(4-trifluoromethyl-phenyl)-pyrimidine (example A.12) (2.73 g, 10.0 mmol) and commercially available 4-bromo-imidazole (2.21 g, 15.0 mmol) according to the general procedure IVa. Obtained as a light brown solid (3.20 g, 84%). MS (ISP) 383.0 [(M+H)+]; mp 166-168° C.