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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1927892Generated: October 31, 2026

(3-Bromophenyl)boronic acid → 2-(3-Bromo-phenyl)-4-(4-chloro-phenyl)-6-methylpyridine

https://huagongshe.com/reaction/1927892

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Bromophenyl)boronic acidHCID 2734318—
Reactant4-(4-Chloro-phenyl)-2-iodo-6-methyl-pyridineHCID 57468642—
Product2-(3-Bromo-phenyl)-4-(4-chloro-phenyl)-6-methylpyridineHCID 57468750—

Reaction Steps

The title compound was prepared from 4-(4-chloro-phenyl)-2-iodo-6-methyl-pyridine (example A.29) (1.5 g, 5 mmol) and commercially available 3-bromo-benzene-boronic acid (1.005 g, 5 mmol) according to the general procedure IVb. Obtained as a white solid (0.15 g, 8.4%). MS (ISP) 358.0 [(M+H)+], 360.0 [(M+2+H)+] and 362.2 [(M+4+H)+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183262B2
Source datasetuspto-grants-2012_05
ORD IDord-707e40d730e544d886a497d315ae4704
Source noteuspto-grants-2012_05