HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dichloropyrimidine → 2'-Chloro-6-trifluoromethyl-4-(4-trifluoromethyl-phenyl)-[2,4']bipyrimidinyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dichloropyrimidine | HCID 77531 | — |
| Reactant | HCID 57468602 | HCID 57468602 | — |
| Product | 2'-Chloro-6-trifluoromethyl-4-(4-trifluoromethyl-phenyl)-[2,4']bipyrimidinyl | HCID 86615444 | — |
Reaction Steps
The title compound was prepared from 2-iodo-4-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-pyrimidine (example A.4) (1.0 g, 2.39 mmol) and 2,4-dichloro-pyrimidine (0.356 g, 2.39 mmol) according to the general procedure IVc. Obtained as an off-white solid (0.49 g, 50%). MS (EI) 404.1 [(M)+]; mp 152° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183262B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-0afa050f157b4b85a3ce33c4c1502bcf |
| Source note | uspto-grants-2012_05 |