HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloropyridine-4-boronic acid → HCID 57468763, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloropyridine-4-boronic acid | HCID 5151595 | — |
| Reactant | 2-Chloro-4-methyl-6-(4-trifluoromethyl-phenyl)-pyrimidine | HCID 57468614 | — |
| Product | HCID 57468763 | HCID 57468763 | — |
Reaction Steps
The title compound was prepared from 2-chloro-4-methyl-6-(4-trifluoromethyl-phenyl)-pyrimidine (example A.12) (0.27 g, 1.0 mmol) and commercially available 2-chloro-pyridine-4-boronic acid (0.21 g, 1.3 mmol) according to the general procedure IVb. Obtained as an off-white solid (0.175 g, 50%). MS (ISP) 350.4 [(M+H)+]; mp 147° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183262B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-99c9b22f548549a98ce69ee21b8a4fa0 |
| Source note | uspto-grants-2012_05 |