(3-Bromophenyl)boronic acid → 2-(3-Bromo-phenyl)-4-(4-chloro-3-methylphenyl)-6-methyl-pyrimidine

Participants

Reaction Steps

The title compound was prepared from 2-chloro-4-(4-chloro-3-methyl-phenyl)-6-methyl-pyrimidine (example A.47) (3.84 g, 15.2 mmol) and commercially available 3-bromo-benzene-boronic acid (3.2 g, 15.9 mmol) according to the general procedure IVb. Obtained as a white solid (2.87 g, 51%). MS (ISP) 375.1 [(M+H)+]; mp 108° C.

Provenance & Evidence