2-Chloro-4-trifluoromethyl-6-(4-trifluoromethylphenyl)-pyridine → 2-(3-Chloro-[1,2,4]triazol-1-yl)-4-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-pyridine

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Reaction Steps

The title compound was prepared from 2-chloro-4-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-pyridine (example A.17) (1.628 g, 5.0 mmol) and commercially available 3-chloro-1H-(1,2,4)triazole (0.776 g, 7 mmol) according to the general procedure IVa. Obtained as a white solid (1.651 g, 84%). MS (ISP) 393.1 [(M+H)+] and 395 [(M+2+H)+].

Provenance & Evidence