5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine → 6-Cyclopropyl-4-(4-trifluoromethyl-phenyl)-[2,3';5',3'']terpyridin-6''-ylamine

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Reaction Steps

The title compound was prepared from 5′-bromo-6-cyclopropyl-4-(4-trifluoromethyl-phenyl)-[2,3′]bipyridinyl (example E.25) (0.15 g, 0.36 mmol) and commercially available 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (0.087 g, 0.40 mmol) according to the general procedure VI. Obtained as a white solid (0.080 g, 51%). MS (ISP) 433.3 [(M+H)+]; mp 207-209° C.

Provenance & Evidence