2-Aminopyrimidine-5-boronic acid, pinacol ester → HCID 60209377, compound

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Reaction Steps

The title compound was prepared from 2-(3-bromo-phenyl)-6-methyl-4-(4-trifluoromethyl-phenyl)-pyridine (example E.21) (0.150 g, 0.39 mmol) and commercially available 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (0.093 g, 0.42 mmol) according to the general procedure VI. Obtained as a white solid (0.10 g, 64%). MS (ISP) 407.3 [(M+H)+]; mp 215-217° C.

Provenance & Evidence