5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine → 6-Cyclopropyl-4-(4-trifluoromethyl-phenyl)-[2,4';2',3'']terpyridin-6''-ylamine

Participants

Reaction Steps

The title compound was prepared from 2′-chloro-6-cyclopropyl-4-(4-trifluoromethyl-phenyl)-[2,4′]bipyridinyl (example E.29) (0.300 g, 0.80 mmol) and commercially available 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (0.229 g, 1.17 mmol) according to the general procedure VI. Obtained as a white solid (0.060 g, 17%). MS (ISP) 433.1 [(M+H)+]; mp 172-174° C.

Provenance & Evidence