N-hydroxy-4-sulfamoylbenzene-1-carboximidamide → HCID 68693992, compound

HRID 1928085Notes

Reaction equation

HRID 1928085 reaction equation
[OH:1][NH:2][C:3](=[NH:14])[C:4]1[CH:9]=[CH:8][C:7]([S:10](=[O:13])(=[O:12])[NH2:11])=[CH:6][CH:5]=1.[Cl:15][C:16]1[CH:17]=[C:18]([C:23]2[CH:28]=[C:27]([C:29]([F:32])([F:31])[F:30])[N:26]=[C:25]([C:33](O)=O)[N:24]=2)[CH:19]=[CH:20][C:21]=1[Cl:22]>>[Cl:15][C:16]1[CH:17]=[C:18]([C:23]2[CH:28]=[C:27]([C:29]([F:32])([F:30])[F:31])[N:26]=[C:25]([C:33]3[O:1][N:2]=[C:3]([C:4]4[CH:9]=[CH:8][C:7]([S:10]([NH2:11])(=[O:12])=[O:13])=[CH:6][CH:5]=4)[N:14]=3)[N:24]=2)[CH:19]=[CH:20][C:21]=1[Cl:22]

Participants

3

Reactant 2

HCID 612025N-hydroxy-4-sulfamoylbenzene-1-carboximidamideHCID 57468718HCID 57468718, compound

Product 1

HCID 68693992HCID 68693992, compound

Procedure

The title compound was prepared from N-hydroxy-4-sulfamoyl-benzamidine [CAS-No. 4476-10-2] (0.16 g, 0.74 mmol) and 4-(3,4-dichloro-phenyl)-6-trifluoromethyl-pyrimidine-2-carboxylic acid (example D.6) (0.17 g, 0.50 mmol) according to the general procedure V. Obtained as a light yellow solid (0.042 g, 16%). MS (ISP) 516.1 [(M+H)+]; mp 302.5° C.

Sources & evidence

ORD record
ord-fb39306527454957a02ca212224d2934
Source dataset
uspto-grants-2012_05
Patent number
US08183262B2

Reaction notes

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