HCID 57468719, compound → HCID 57468875, compound

HRID 1928091Notes

Reaction equation

HRID 1928091 reaction equation
[OH:1][NH:2][C:3](=[NH:14])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([S:10](=[O:13])(=[O:12])[NH2:11])[CH:5]=1.[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([C:22]2[CH:27]=[C:26]([C:28]([F:31])([F:30])[F:29])[N:25]=[C:24]([C:32](O)=O)[N:23]=2)=[CH:18][C:17]=1[CH3:35]>>[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([C:22]2[CH:27]=[C:26]([C:28]([F:30])([F:29])[F:31])[N:25]=[C:24]([C:32]3[O:1][N:2]=[C:3]([C:4]4[CH:5]=[C:6]([S:10]([NH2:11])(=[O:12])=[O:13])[CH:7]=[CH:8][CH:9]=4)[N:14]=3)[N:23]=2)=[CH:18][C:17]=1[CH3:35]

Participants

3

Reactant 2

HCID 57468719HCID 57468719, compoundHCID 178513322HCID 178513322, compound

Product 1

HCID 57468875HCID 57468875, compound

Procedure

The title compound was prepared from N-hydroxy-3-sulfamoyl-benzamidine [CAS-No. 9000-88-7] (0.16 g, 0.74 mmol) and 4-(4-chloro-3-methyl-phenyl)-6-trifluoromethyl-pyrimidine-2-carboxylic acid (example D.7) (0.16 g, 0.50 mmol) according to the general procedure V. Obtained as a white solid (0.046 g, 19%). MS (ISP) 496.2 [(M+H)+]; mp 246° C.

Sources & evidence

ORD record
ord-9533f3b09e4f42eab91867c2e02bbd53
Source dataset
uspto-grants-2012_05
Patent number
US08183262B2

Reaction notes

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