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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1928155Generated: October 31, 2026

HCID 57468728, compound → HCID 60209427, compound

https://huagongshe.com/reaction/1928155

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57468728HCID 57468728—
ReactantN-tert-butyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-sulfonamideHCID 57468817—
ProductHCID 60209427HCID 60209427—

Reaction Steps

The title compound was prepared from 2-(3-bromo-phenyl)-4-(4-chloro-phenyl)-6-trifluoromethyl-pyrimidine (example E.4) (0.414 g, 1.0 mmol) and N-tert-butyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-thiophene-2-sulfonamide (example F.1) (0.41 g, 1.2 mmol) according to the general procedure VI. Obtained as a white solid (0.22 g, 40%). MS (ISN) 550.2 [(M−H)−]; mp 197.5° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183262B2
Source datasetuspto-grants-2012_05
ORD IDord-53228de7fb7e404588490b283a7bb526
Source noteuspto-grants-2012_05