HCID 57468724, compound → HCID 57469008, compound

HRID 1928272Notes

Reaction equation

HRID 1928272 reaction equation
[OH:1][NH:2][C:3](=[NH:14])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([S:10](=[O:13])(=[O:12])[NH2:11])[CH:5]=1.[F:15][C:16]([F:37])([F:36])[C:17]1[CH:22]=[C:21]([C:23]2[CH:28]=[CH:27][C:26]([C:29]([F:32])([F:31])[F:30])=[CH:25][CH:24]=2)[N:20]=[C:19]([C:33](O)=O)[CH:18]=1>>[F:37][C:16]([F:15])([F:36])[C:17]1[CH:22]=[C:21]([C:23]2[CH:28]=[CH:27][C:26]([C:29]([F:30])([F:31])[F:32])=[CH:25][CH:24]=2)[N:20]=[C:19]([C:33]2[O:1][N:2]=[C:3]([C:4]3[CH:5]=[C:6]([S:10]([NH2:11])(=[O:12])=[O:13])[CH:7]=[CH:8][CH:9]=3)[N:14]=2)[CH:18]=1

Participants

3

Reactant 2

HCID 57468724HCID 57468724, compoundHCID 178513322HCID 178513322, compound

Product 1

HCID 57469008HCID 57469008, compound

Procedure

The title compound was prepared from N-hydroxy-3-sulfamoyl-benzamidine [CAS-No. 9000-88-7] (0.230 g, 1.06 mmol) and 4-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid (example D.12) (0.30 g, 1.00 mmol) according to the general procedure V. Obtained as a white solid (0.100 g, 22%). MS (ISP) 513.2 [(M+H)+]; mp 211° C.

Sources & evidence

ORD record
ord-cb18adc787af421caf51b45ed1fc846c
Source dataset
uspto-grants-2012_05
Patent number
US08183262B2

Reaction notes

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