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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1928280Generated: October 31, 2026

2,4-Dibromo-1,3-thiazole → HCID 57469013, compound

https://huagongshe.com/reaction/1928280

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-Dibromo-1,3-thiazoleHCID 2763297—
Reactant2-Iodo-6-methyl-4-(4-trifluoromethyl-phenyl)pyridineHCID 57468645—
ProductHCID 57469013HCID 57469013—

Reaction Steps

The title compound was prepared from 2-iodo-6-methyl-4-(4-trifluoromethyl-phenyl)-pyridine (example A.31) (4.0 g, 9.36 mmol) and commercially available 2,4-dibromothiazole (2.53 g, 10.4 mmol) according to the general procedure IVc protocol b. Obtained as a side product as a light yellow solid (0.065 g, 2%). MS (ISP) 321.2 [(M+H)+]; mp 103° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183262B2
Source datasetuspto-grants-2012_05
ORD IDord-2d44a1ee9c234904b89a1cf6507441d8
Source noteuspto-grants-2012_05