3-(tert-Butylaminosulphonyl)benzeneboronic acid → N-tert-butyl-3-[6'-methyl-4'-(4-trifluoromethylphenyl)-[2,2']bipyridinyl-6-yl]-benzenesulfonamide

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Reaction Steps

The title compound was prepared from 6′-bromo-6-methyl-4-(4-trifluoromethyl-phenyl)-[2,2′]bipyridinyl (example E.26) (0.65 g, 1.65 mmol) and commercially available 3-(tert-butylsulfamoyl)-benzeneboronic acid (0.468 g, 1.82 mmol) according to the general procedure VI. Obtained as a white solid (0.10 g, 12%) and additional off-white solid (0.57 g, 66%). MS (ISP) 526.2 [(M+H)+]; mp 183° C.

Provenance & Evidence