HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Methylsulfonyl)phenylboronic acid → HCID 24760662, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Methylsulfonyl)phenylboronic acid | HCID 2773542 | — |
| Reactant | 2-Chloro-4-[6-methyl-4-(4-trifluoromethylphenyl)-pyridin-2-yl]-pyrimidine | HCID 57468797 | — |
| Product | HCID 24760662 | HCID 24760662 | — |
Reaction Steps
The title compound was prepared from 2-chloro-4-[6-methyl-4-(4-trifluoromethyl-phenyl)-pyridin-2-yl]-pyrimidine (example E.83) (0.350 g, 1.0 mmol) and commercially available (3-methylsulfonylphenyl)boronic acid (0.220 g, 1.0 mmol) according to the general procedure VI. Obtained as an off-white solid (0.280 g, 59%). MS (ISP) 470.1 [(M+H)+]; mp 208° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183262B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-d517d66f5afd48d1996a4c70714cefeb |
| Source note | uspto-grants-2012_05 |