Dichloromethane → 3-fluoro-N-[3-(3-pyridin-4-yl-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]thiazin-2-yl)-phenyl]-benzenesulfonamide

HRID 192862Notes

Reaction equation

HRID 192862 reaction equation
[Cl:34][CH2:35][Cl:36].[F:23][c:24]1[cH:25][c:26]([S:30](=[O:31])(=[O:32])[Cl:33])[cH:27][cH:28][cH:29]1.[n:1]1[cH:2][cH:3][c:4](-[c:7]2[c:8](-[c:16]3[cH:17][c:18]([NH2:22])[cH:19][cH:20][cH:21]3)[n:9][n:10]3[c:11]2[S:12][CH2:13][CH2:14][CH2:15]3)[cH:5][cH:6]1>>[n:1]1[cH:2][cH:3][c:4](-[c:7]2[c:8](-[c:16]3[cH:17][c:18]([NH:22][S:30]([c:26]4[cH:25][c:24]([F:23])[cH:29][cH:28][cH:27]4)(=[O:31])=[O:32])[cH:19][cH:20][cH:21]3)[n:9][n:10]3[c:11]2[S:12][CH2:13][CH2:14][CH2:15]3)[cH:5][cH:6]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 27342583-Fluorobenzenesulfonyl ChlorideHCID 674228643-(3-Pyridin-4-yl-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]thiazin-2-yl)-phenylamine

Product 1

HCID 467018383-fluoro-N-[3-(3-pyridin-4-yl-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]thiazin-2-yl)-phenyl]-benzenesulfonamide

Sources & evidence

ORD record
ord-b906754bea09477984b5bd9ef8160205
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…