L-Glutamic Acid → Strontium glutamate

HRID 1928692Notes

Reaction equation

HRID 1928692 reaction equation
O.O.O.O.O.O.[NH2:7][C@H:8]([C:14]([O-:16])=[O:15])[CH2:9][CH2:10][C:11]([O-:13])=[O:12].[Sr+2:17].[OH-].[Sr+2].[OH-].N[C@H](C(O)=O)CCC(O)=O>>[NH2:7][C@H:8]([C:14]([O-:16])=[O:15])[CH2:9][CH2:10][C:11]([O-:13])=[O:12].[Sr+2:17]

Participants

4

Reactant 3

HCID 33032L-Glutamic AcidHCID 87672Strontium hydroxideHCID 86616728strontium L-glutamate hexahydrate

Product 1

HCID 11390644Strontium glutamate

Procedure

In a method according to the present invention strontium L-glutamate hexahydrate has been prepared by reacting strontium hydroxide with glutamic acid at a temperature in a range of from about 120° C. to about 135° C. and at a pressure of from about 1 to about 1.7 bar, optionally under an inert gas atmosphere, for a time period of from about 15 min to about 60 min to obtain strontium glutamate. The method may further involve a step of filtering the hot reaction mixture immediately after heating is stopped to remove precipitated calcium carbonate from the reaction mixture. Further details and guidelines for optimization of the reaction appears from Example 8.

Workup

  1. customhas been prepared
  2. customof from about 120° C. to about 135° C.

Sources & evidence

ORD record
ord-882f9530f65c4302b51111ff3c044e15
Source dataset
uspto-grants-2012_05
Patent number
US08183409B2

Reaction notes

Loading…