2-Chloro-6-nitroquinoline → Rac-n2-(8-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-quinoline-2,6-diamine

HRID 1928717Notes

Reaction equation

HRID 1928717 reaction equation
Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([N+:12]([O-])=O)[CH:8]=2)[N:3]=1.[CH3:15][O:16][C:17]1[CH:18]=[CH:19][CH:20]=[C:21]2[C:26]=1[CH:25]([NH2:27])[CH2:24][CH2:23][CH2:22]2>>[CH3:15][O:16][C:17]1[CH:18]=[CH:19][CH:20]=[C:21]2[C:26]=1[CH:25]([NH:27][C:2]1[CH:11]=[CH:10][C:9]3[C:4](=[CH:5][CH:6]=[C:7]([NH2:12])[CH:8]=3)[N:3]=1)[CH2:24][CH2:23][CH2:22]2

Participants

3

Reactant 2

HCID 109217232-Chloro-6-nitroquinolineHCID 221473568-Methoxy-1,2,3,4-tetrahydronaphthalen-1-amine

Product 1

HCID 57860959Rac-n2-(8-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-quinoline-2,6-diamine

Procedure

The title compound was prepared in accordance with the general method described in example 2 from 2-chloro-6-nitro-quinoline and rac-8-methoxy-1,2,3,4-tetrahydronaphthalen-1-amine (CAS no. 535935-61-6); MS: m/e=320.3 (M+H+).

Sources & evidence

ORD record
ord-3974d8716e4647d9aac1447d5296f138
Source dataset
uspto-grants-2012_05
Patent number
US08183380B2

Reaction notes

Loading…