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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1928718Generated: November 2, 2026

Isopropyl isocyanate → Rac-1-isopropyl-3-[2-(8-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylamino)-quinolin-6-yl]-urea

https://huagongshe.com/reaction/1928718

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropyl isocyanateHCID 61277—
ReactantRac-n2-(8-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-quinoline-2,6-diamineHCID 57860959—
ProductRac-1-isopropyl-3-[2-(8-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylamino)-quinolin-6-yl]-ureaHCID 68630475—

Reaction Steps

The title compound was prepared in accordance with the general method described in example 3 from rac-N2-(8-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-quinoline-2,6-diamine and isopropyl isocyanate; MS: m/e=405.5 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183380B2
Source datasetuspto-grants-2012_05
ORD IDord-1ea7577e776647ec832d0ea7dfbf415b
Source noteuspto-grants-2012_05