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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1928720Generated: October 31, 2026

2-Methoxyethylamine → 1-[2-((R)-Indan-1-ylamino)-quinolin-6-yl]-3-(2-methoxy-ethyl)-urea

https://huagongshe.com/reaction/1928720

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethoxyethylamineHCID 8018—
ReactantTriphosgeneHCID 94429—
Reactant(R)-N2-Indan-1-yl-quinoline-2,6-diamineHCID 57860958—
Product1-[2-((R)-Indan-1-ylamino)-quinolin-6-yl]-3-(2-methoxy-ethyl)-ureaHCID 44217472—

Reaction Steps

The title compound was prepared in accordance with the general method 4 described in example 16 from bis(trichloromethyl) carbonate, 2-methoxyethylamine and (R)—N2-indan-1-yl-quinoline-2,6-diamine; MS: m/e=377.5 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183380B2
Source datasetuspto-grants-2012_05
ORD IDord-e16f190caaeb4014acd5ecfd83709631
Source noteuspto-grants-2012_05