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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 192875Generated: October 25, 2026

Dichloromethane → Methyl {8-fluoro-2-[4-(3,4-difluorophenyl)-1-piperazinyl]-3-[2-methoxy-5-(trifluoromethyl)-phenyl]-3,4-dihydro-4-quinazolinyl}acetate

https://huagongshe.com/reaction/192875

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
Reactant1-(3,4-Difluorophenyl)piperazineHCID 2783122—
ReactantMethyl 3-[3-fluoro-2-[[2-methoxy-5-(trifluoromethyl)phenyl]iminomethylideneamino]phenyl]prop-2-enoateHCID 72436574—
ProductMethyl {8-fluoro-2-[4-(3,4-difluorophenyl)-1-piperazinyl]-3-[2-methoxy-5-(trifluoromethyl)-phenyl]-3,4-dihydro-4-quinazolinyl}acetateHCID 58824001—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-86fb0a36c709495690f14ea12bbcaa0a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)