Dimethylsulphamoyl chloride → HCID 68639281, compound
Reaction equation
[CH3:1][N:2]([CH3:7])[S:3](Cl)(=[O:5])=[O:4].[Cl:8][C:9]1[CH:17]=[C:16]([Cl:18])[C:15]([O:19][CH3:20])=[C:14]2[C:10]=1[CH2:11][CH2:12][CH:13]2[NH:21][C:22]1[CH:31]=[CH:30][C:29]2[C:24](=[CH:25][CH:26]=[C:27]([NH2:32])[CH:28]=2)[N:23]=1>>[Cl:8][C:9]1[CH:17]=[C:16]([Cl:18])[C:15]([O:19][CH3:20])=[C:14]2[C:10]=1[CH2:11][CH2:12][CH:13]2[NH:21][C:22]1[CH:31]=[CH:30][C:29]2[C:24](=[CH:25][CH:26]=[C:27]([NH:32][S:3]([N:2]([CH3:7])[CH3:1])(=[O:5])=[O:4])[CH:28]=2)[N:23]=1Participants
3
Procedure
The title compound was prepared in accordance with the general method described in example 66 from dimethylsulfamoylchloride and rac-N2-(4,6-dichloro-7-methoxy-indan-1-yl)-quinoline-2,6-diamine; MS: m/e=482.6 (M+H+).
Sources & evidence
- ORD record
- ord-29e413a2383b49478d956b2f793e0706
- Source dataset
- uspto-grants-2012_05
- Patent number
- US08183380B2
Reaction notes
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