Triethylamine → HCID 57860968, compound

Participants

Reaction Steps

(R)—N2-Indan-1-yl-quinoline-2,6-diamine (0.09 g, 0.33 mmol) and dimethylamino pyridinium N-tert butoxycarbonyl sulfamide (0.12 g, 0.36 mmol) were dissolved in acetonitrile (2.0 mL). After addition of triethylamine (0.05 mL, 0.36 mmol) the reaction mixture was heated to reflux for 16 h. The solvent was removed and the residue subjected to column chromatography (silica gel, heptane/ethyl acetate=9:1/4:1/1:1). The title compound was obtained as a yellow solid (15 mg; 10%); MS: m/e=455.7 (M+H+).

Provenance & Evidence