1-Pyrrolidinesulfonyl chloride → HCID 44218873, compound
Reaction equation
[N:1]1([S:6](Cl)(=[O:8])=[O:7])[CH2:5][CH2:4][CH2:3][CH2:2]1.[C@H:10]1([NH:19][C:20]2[CH:29]=[CH:28][C:27]3[C:22](=[CH:23][CH:24]=[C:25]([NH2:30])[CH:26]=3)[N:21]=2)[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12][CH2:11]1>>[C@H:10]1([NH:19][C:20]2[CH:29]=[CH:28][C:27]3[C:22](=[CH:23][CH:24]=[C:25]([NH:30][S:6]([N:1]4[CH2:5][CH2:4][CH2:3][CH2:2]4)(=[O:8])=[O:7])[CH:26]=3)[N:21]=2)[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12][CH2:11]1Participants
3
Procedure
The title compound was prepared in accordance with the general method described in example 66 from pyrrolidine-1-sulfonyl chloride and (R)—N2-indan-1-yl-quinoline-2,6-diamine; MS: m/e=409.6 (M+H+).
Sources & evidence
- ORD record
- ord-f40f9003f7c344848298cd499e12f3eb
- Source dataset
- uspto-grants-2012_05
- Patent number
- US08183380B2
Reaction notes
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