4-methylpiperazine-1-sulfonyl Chloride → HCID 44219026, compound

HRID 1928775Notes

Reaction equation

HRID 1928775 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([S:8](Cl)(=[O:10])=[O:9])[CH2:4][CH2:3]1.[C@H:12]1([NH:21][C:22]2[CH:31]=[CH:30][C:29]3[C:24](=[CH:25][CH:26]=[C:27]([NH2:32])[CH:28]=3)[N:23]=2)[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH2:14][CH2:13]1>>[C@H:12]1([NH:21][C:22]2[CH:31]=[CH:30][C:29]3[C:24](=[CH:25][CH:26]=[C:27]([NH:32][S:8]([N:5]4[CH2:6][CH2:7][N:2]([CH3:1])[CH2:3][CH2:4]4)(=[O:10])=[O:9])[CH:28]=3)[N:23]=2)[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH2:14][CH2:13]1

Participants

3

Procedure

The title compound was prepared in accordance with the general method described in example 66 from 4-methyl-piperazine-1-sulfonyl chloride and (R)—N2-indan-1-yl-quinoline-2,6-diamine; MS: m/e=438.8 (M+H+).

Sources & evidence

ORD record
ord-93bc104fb338489f9b20bb7600f07eab
Source dataset
uspto-grants-2012_05
Patent number
US08183380B2

Reaction notes

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