(R)-N2-Indan-1-yl-quinoline-2,6-diamine → HCID 68910966, compound

HRID 1928778Notes

Reaction equation

HRID 1928778 reaction equation
FC(F)(F)S([O-])(=O)=O.C[N+]1[CH:14]=[CH:13][N:12]([S:15](=[O:25])(=[O:24])[N:16]([CH3:23])[CH:17]2[CH2:22][CH2:21][O:20][CH2:19][CH2:18]2)C=1.[C@H:26]1([NH:35][C:36]2[CH:45]=[CH:44][C:43]3[C:38](=[CH:39][CH:40]=C(N)C=3)[N:37]=2)[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH2:28][CH2:27]1>>[C@H:26]1([NH:35][C:36]2[CH:45]=[CH:44][C:43]3[C:38](=[CH:39][CH:40]=[C:13]([NH:12][S:15]([N:16]([CH3:23])[CH:17]4[CH2:18][CH2:19][O:20][CH2:21][CH2:22]4)(=[O:24])=[O:25])[CH:14]=3)[N:37]=2)[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH2:28][CH2:27]1

Participants

3

Reactant 2

HCID 57860958(R)-N2-Indan-1-yl-quinoline-2,6-diamineHCID 86634169HCID 86634169, compound

Product 1

HCID 68910966HCID 68910966, compound

Procedure

The title compound was prepared in accordance with step C of the general method described in example 76 from 1-methyl-3-[methyl-(tetrahydro-pyran-4-yl)-sulfamoyl]-3H-imidazol-1-ium trifluoromethanesulfonate and (R)—N2-indan-1-yl-quinoline-2,6-diamine; MS: m/e=453.8 (M+H+).

Sources & evidence

ORD record
ord-67da396c66f34a2a825970ef74d9fc82
Source dataset
uspto-grants-2012_05
Patent number
US08183380B2

Reaction notes

Loading…