8-Oxa-3-aza-bicyclo(3.2.1)octane hydrochloride → 3-(Imidazole-1-sulfonyl)-8-oxa-3-aza-bicyclo[3.2.1]octane

HRID 1928790Notes

Reaction equation

HRID 1928790 reaction equation
Cl.[CH:2]12[O:9][CH:6]([CH2:7][CH2:8]1)[CH2:5][NH:4][CH2:3]2.FC(F)(F)S([O-])(=O)=O.[N:18]1([S:23](N2C=C[NH+](C)C2)(=[O:25])=[O:24])[CH:22]=[CH:21][N:20]=[CH:19]1>>[N:18]1([S:23]([N:4]2[CH2:3][CH:2]3[O:9][CH:6]([CH2:7][CH2:8]3)[CH2:5]2)(=[O:25])=[O:24])[CH:22]=[CH:21][N:20]=[CH:19]1

Participants

3

Reactant 2

HCID 219835368-Oxa-3-aza-bicyclo(3.2.1)octane hydrochlorideHCID 866341663-(1H-Imidazol-1-ylsulfonyl)-1-methyl-1H-imidazolium trifluoromethanesulfonate

Product 1

HCID 689157153-(Imidazole-1-sulfonyl)-8-oxa-3-aza-bicyclo[3.2.1]octane

Procedure

3-(Imidazole-1-sulfonyl)-8-oxa-3-aza-bicyclo[3.2.1]octane was prepared in accordance with step A of the general method described in example 76 8-oxa-3-aza-bicyclo[3.2.1]octane hydrochloride and 3-(1H-imidazol-1-ylsulfonyl)-1-methyl-1H-imidazolium trifluoromethanesulfonate; MS: m/e=244.4 (M+H+).

Sources & evidence

ORD record
ord-7af0d1b85ea94b398955d1c3be456cd2
Source dataset
uspto-grants-2012_05
Patent number
US08183380B2

Reaction notes

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