N-cyclopropylsulfamoyl chloride → HCID 44218575, compound
Reaction equation
[CH:1]1([NH:4][S:5](Cl)(=[O:7])=[O:6])[CH2:3][CH2:2]1.[C@H:9]1([NH:18][C:19]2[CH:28]=[CH:27][C:26]3[C:21](=[CH:22][CH:23]=[C:24]([NH2:29])[CH:25]=3)[N:20]=2)[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH2:11][CH2:10]1>>[CH:1]1([NH:4][S:5]([NH:29][C:24]2[CH:25]=[C:26]3[C:21](=[CH:22][CH:23]=2)[N:20]=[C:19]([NH:18][C@H:9]2[C:17]4[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=4)[CH2:11][CH2:10]2)[CH:28]=[CH:27]3)(=[O:7])=[O:6])[CH2:3][CH2:2]1Participants
3
Procedure
The title compound was prepared in accordance with the general method described in example 66 from cyclopropylsulfamoylchloride and (R)—N2-indan-1-yl-quinoline-2,6-diamine; MS: m/e=395.6 (M+H+).
Sources & evidence
- ORD record
- ord-e5df3646d1de413fa8f08b9bcd78c873
- Source dataset
- uspto-grants-2012_05
- Patent number
- US08183380B2
Reaction notes
Loading…