4-Morpholineacetic acid → HCID 68910780, compound

HRID 1928818Notes

Reaction equation

HRID 1928818 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:12]=1[CH:11]([NH:13][C:14]1[CH:23]=[CH:22][C:21]3[C:16](=[CH:17][CH:18]=[C:19]([NH2:24])[CH:20]=3)[N:15]=1)[CH2:10][CH2:9][CH2:8]2.[N:25]1([CH2:31][C:32](O)=[O:33])[CH2:30][CH2:29][O:28][CH2:27][CH2:26]1>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:12]=1[CH:11]([NH:13][C:14]1[CH:23]=[CH:22][C:21]3[C:16](=[CH:17][CH:18]=[C:19]([NH:24][C:32](=[O:33])[CH2:31][N:25]4[CH2:30][CH2:29][O:28][CH2:27][CH2:26]4)[CH:20]=3)[N:15]=1)[CH2:10][CH2:9][CH2:8]2

Participants

3

Reactant 2

HCID 4389684-Morpholineacetic acidHCID 57860959Rac-n2-(8-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-quinoline-2,6-diamine

Product 1

HCID 68910780HCID 68910780, compound

Procedure

The title compound was prepared in accordance with the general method 14 described in example 119 from rac-N2-(8-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-quinoline-2,6-diamine and morpholin-4-yl-acetic acid; MS: m/e=447.3 (M+H+).

Sources & evidence

ORD record
ord-d6b836479f264536982390996de30cf4
Source dataset
uspto-grants-2012_05
Patent number
US08183380B2

Reaction notes

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