1-Methylpiperidine-4-carboxylic acid → HCID 91155645, compound

HRID 1928822Notes

Reaction equation

HRID 1928822 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:11]=1[CH:10]([NH:12][C:13]1[CH:22]=[CH:21][C:20]3[C:15](=[CH:16][CH:17]=[C:18]([NH2:23])[CH:19]=3)[N:14]=1)[CH2:9][CH2:8]2.[CH3:24][N:25]1[CH2:30][CH2:29][CH:28]([C:31](O)=[O:32])[CH2:27][CH2:26]1>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:11]=1[CH:10]([NH:12][C:13]1[CH:22]=[CH:21][C:20]3[C:15](=[CH:16][CH:17]=[C:18]([NH:23][C:31]([CH:28]4[CH2:29][CH2:30][N:25]([CH3:24])[CH2:26][CH2:27]4)=[O:32])[CH:19]=3)[N:14]=1)[CH2:9][CH2:8]2

Participants

3

Reactant 2

HCID 27369391-Methylpiperidine-4-carboxylic acidHCID 57860964Rac-n2-(7-methoxy-indan-1-yl)-quinoline-2,6-diamine

Product 1

HCID 91155645HCID 91155645, compound

Procedure

The title compound was prepared in accordance with the general method 14 described in example 119 from rac-N2-(7-methoxy-indan-1-yl)-quinoline-2,6-diamine (Example 172) and 1-methyl-piperidine-4-carboxylic acid; MS: m/e=414.3 (M+H+).

Sources & evidence

ORD record
ord-d70c971783e547be886c3ce0c96c50da
Source dataset
uspto-grants-2012_05
Patent number
US08183380B2

Reaction notes

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