Cyclopropanecarboxylic acid → HCID 91389794, compound
Reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:11]=1[CH:10]([NH:12][C:13]1[CH:22]=[CH:21][C:20]3[C:15](=[CH:16][CH:17]=[C:18]([NH2:23])[CH:19]=3)[N:14]=1)[CH2:9][CH2:8]2.[CH:24]1([C:27](O)=[O:28])[CH2:26][CH2:25]1>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:11]=1[CH:10]([NH:12][C:13]1[CH:22]=[CH:21][C:20]3[C:15](=[CH:16][CH:17]=[C:18]([NH:23][C:27]([CH:24]4[CH2:26][CH2:25]4)=[O:28])[CH:19]=3)[N:14]=1)[CH2:9][CH2:8]2Participants
3
Procedure
The title compound was prepared in accordance with the general method 14 described in example 119 from rac-N2-(7-methoxy-indan-1-yl)-quinoline-2,6-diamine (Example 172) and cyclopropyl carboxylic acid; MS: m/e=374.4 (M+H+).
Sources & evidence
- ORD record
- ord-aae64e786d9f4b779adf1343148cb10c
- Source dataset
- uspto-grants-2012_05
- Patent number
- US08183380B2
Reaction notes
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