(4-Methylpiperazin-1-yl)acetic acid → HCID 68633182, compound

HRID 1928835Notes

Reaction equation

HRID 1928835 reaction equation
[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[CH:7]([NH:11][C:12]1[CH:21]=[CH:20][C:19]3[C:14](=[CH:15][CH:16]=[C:17]([NH2:22])[CH:18]=3)[N:13]=1)[CH2:6][CH2:5]2.[CH3:23][N:24]1[CH2:29][CH2:28][N:27]([CH2:30][C:31](O)=[O:32])[CH2:26][CH2:25]1>>[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[CH:7]([NH:11][C:12]1[CH:21]=[CH:20][C:19]3[C:14](=[CH:15][CH:16]=[C:17]([NH:22][C:31](=[O:32])[CH2:30][N:27]4[CH2:28][CH2:29][N:24]([CH3:23])[CH2:25][CH2:26]4)[CH:18]=3)[N:13]=1)[CH2:6][CH2:5]2

Participants

3

Reactant 2

HCID 2762732(4-Methylpiperazin-1-yl)acetic acidHCID 68638772HCID 68638772, compound

Product 1

HCID 68633182HCID 68633182, compound

Procedure

The title compound was prepared in accordance with the general method 14 described in example 119 from rac-N2-(5-fluoro-indan-1-yl)-quinoline-2,6-diamine and (4-methyl-piperazin-1-yl)-acetic acid; MS: m/e=434.3 (M+H+).

Sources & evidence

ORD record
ord-0e92981f25e1408dbbbd22d51d8aae10
Source dataset
uspto-grants-2012_05
Patent number
US08183380B2

Reaction notes

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