2-Chloro-6-nitroquinoline → HCID 68632105, compound
Reaction equation
Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([N+:12]([O-])=O)[CH:8]=2)[N:3]=1.[F:15][C:16]1[CH:17]=[CH:18][CH:19]=[C:20]2[C:24]=1[CH:23]([NH2:25])[CH2:22][CH2:21]2>>[F:15][C:16]1[CH:17]=[CH:18][CH:19]=[C:20]2[C:24]=1[CH:23]([NH:25][C:2]1[CH:11]=[CH:10][C:9]3[C:4](=[CH:5][CH:6]=[C:7]([NH2:12])[CH:8]=3)[N:3]=1)[CH2:22][CH2:21]2Participants
3
Procedure
Step C+D: The title compound was prepared in accordance with the general method described in example 2 from 2-chloro-6-nitro-quinoline and rac-7-fluoro-indan-1-ylamine; MS: m/e=294.3 (M+H+).
Sources & evidence
- ORD record
- ord-b5c7aa41aefd4ee393abba8fc69ab5a1
- Source dataset
- uspto-grants-2012_05
- Patent number
- US08183380B2
Reaction notes
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