[4-(Propan-2-yl)piperazin-1-yl]acetic acid → HCID 68632280, compound

HRID 1928840Notes

Reaction equation

HRID 1928840 reaction equation
[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[CH:7]([NH:11][C:12]1[CH:21]=[CH:20][C:19]3[C:14](=[CH:15][CH:16]=[C:17]([NH2:22])[CH:18]=3)[N:13]=1)[CH2:6][CH2:5]2.[CH:23]([N:26]1[CH2:31][CH2:30][N:29]([CH2:32][C:33](O)=[O:34])[CH2:28][CH2:27]1)([CH3:25])[CH3:24]>>[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[CH:7]([NH:11][C:12]1[CH:21]=[CH:20][C:19]3[C:14](=[CH:15][CH:16]=[C:17]([NH:22][C:33](=[O:34])[CH2:32][N:29]4[CH2:30][CH2:31][N:26]([CH:23]([CH3:24])[CH3:25])[CH2:27][CH2:28]4)[CH:18]=3)[N:13]=1)[CH2:6][CH2:5]2

Participants

3

Reactant 2

HCID 2759512[4-(Propan-2-yl)piperazin-1-yl]acetic acidHCID 68638772HCID 68638772, compound

Product 1

HCID 68632280HCID 68632280, compound

Procedure

The title compound was prepared in accordance with the general method 14 described in example 119 from rac-N2-(5-fluoro-indan-1-yl)-quinoline-2,6-diamine and (4-isopropyl-piperazin-1-yl)-acetic acid (CAS no: 95470-68-1); MS: m/e=462.5 (M+H+).

Sources & evidence

ORD record
ord-1f5506eba5f44a829282aefbf76c4566
Source dataset
uspto-grants-2012_05
Patent number
US08183380B2

Reaction notes

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