4-Amino-1-methylpiperidine → HCID 178480459, compound

HRID 1928844Notes

Reaction equation

HRID 1928844 reaction equation
I.[C@H:2]1([NH:11][C:12]2[CH:21]=[CH:20][C:19]3[C:14](=[CH:15][CH:16]=[C:17]([NH:22][C:23](=[NH:26])SC)[CH:18]=3)[N:13]=2)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1.[CH3:27][N:28]1[CH2:33][CH2:32][CH:31]([NH2:34])[CH2:30][CH2:29]1>>[C@H:2]1([NH:11][C:12]2[CH:21]=[CH:20][C:19]3[C:14](=[CH:15][CH:16]=[C:17]([NH:22][C:23]([NH:34][CH:31]4[CH2:32][CH2:33][N:28]([CH3:27])[CH2:29][CH2:30]4)=[NH:26])[CH:18]=3)[N:13]=2)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 27375314-Amino-1-methylpiperidineHCID 178503968HCID 178503968, compound

Product 1

HCID 178480459HCID 178480459, compound

Procedure

The title compound was prepared in accordance with the general method 16 described in example 151 from 1-[2-((R)-indan-1-ylamino)-quinolin-6-yl]-2-methyl-isothiourea hydroiodide and 1-methylpiperidine-4-amine; MS: m/e=415.3 (M+H+).

Sources & evidence

ORD record
ord-e89970dafaa543c58e1f067f3cf80f4b
Source dataset
uspto-grants-2012_05
Patent number
US08183380B2

Reaction notes

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