Cyclopropylamine → HCID 178511934, compound

HRID 1928845Notes

Reaction equation

I.[C@H:2]1([NH:11][C:12]2[CH:21]=[CH:20][C:19]3[C:14](=[CH:15][CH:16]=[C:17]([NH:22][C:23](=[NH:26])SC)[CH:18]=3)[N:13]=2)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1.[CH:27]1([NH2:30])[CH2:29][CH2:28]1>>[CH:27]1([NH:30][C:23]([NH:22][C:17]2[CH:18]=[C:19]3[C:14](=[CH:15][CH:16]=2)[N:13]=[C:12]([NH:11][C@H:2]2[C:10]4[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=4)[CH2:4][CH2:3]2)[CH:21]=[CH:20]3)=[NH:26])[CH2:29][CH2:28]1

Participants

Reactant 2

HCID 69828Cyclopropylamine

HCID 178503968HCID 178503968, compound

Product 1

HCID 178511934HCID 178511934, compound

Procedure

The title compound was prepared in accordance with the general method 16 described in example 151 from 1-[2-((R)-indan-1-ylamino)-quinolin-6-yl]-2-methyl-isothiourea hydroiodide and cyclopropylamine; MS: m/e=358.4 (M+H+).

Sources & evidence

ORD record: ord-230bd62e1d6e4a74ab0fc834077a11cc
Source dataset: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08183380B2

Reaction notes

Loading…