HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphosgene → Rac-1-[2-(6-fluoro-indan-1-ylamino)-quinolin-6-yl]-3-(1-isopropyl-piperidin-4-yl)-urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphosgene | HCID 94429 | — |
| Reactant | 1-(Propan-2-yl)piperidin-4-amine | HCID 3163333 | — |
| Reactant | Rac-n2-(6-fluoro-indan-1-yl)-quinoline-2,6-diamine | HCID 68639984 | — |
| Product | Rac-1-[2-(6-fluoro-indan-1-ylamino)-quinolin-6-yl]-3-(1-isopropyl-piperidin-4-yl)-urea | HCID 68632064 | — |
Reaction Steps
The title compound was prepared in accordance with the general method 4 described in example 16 from bis(trichloromethyl) carbonate, 1-isopropyl-piperidin-4-ylamine (CAS no: 127285-08-9) and rac-N2-(6-fluoro-indan-1-yl)-quinoline-2,6-diamine; MS: m/e=462.5 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183380B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-76ac75f0abb6499e9d3ffd66e85b3d5c |
| Source note | uspto-grants-2012_05 |