HCID 86634185, compound → HCID 68631193, compound

Participants

Reaction Steps

A mixture of the above described 4-(2-methoxy-ethoxy)-benzofuran-3-one oxime (1.19 g, 5 mmol) in methanol (100 mL) and tetrahydrofuran (100 mL) with 10% palladium on carbon (1.42 g) was hydrogenated at 23° C. and atmospheric pressure for 5 days. Filtered the catalyst off, washed with tetrahydrofuran, evaporated the filtrate totally and dried in high vacuum to give the title compound as a red oil (1.15 g, 90%, ca. 90% purity, contains residual starting material); MS: m/e=193.1 (M−NH2+H+).

Provenance & Evidence