HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrophenyl chloroformate → HCID 68631842, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrophenyl chloroformate | HCID 82129 | — |
| Reactant | 1-(Propan-2-yl)piperidin-4-amine dihydrochloride | HCID 17750340 | — |
| Reactant | HCID 68913498 | HCID 68913498 | — |
| Product | HCID 68631842 | HCID 68631842 | — |
Reaction Steps
The title compound was prepared from rac-N2-[4-(2-methoxy-ethoxy)-2,3-dihydro-benzofuran-3-yl]-quinoline-2,6-diamine (Example 174) (200 mg, 0.57 mmol), 4-nitrophenyl chloroformate (115 mg, 0.57 mmol) and 1-isopropyl-piperidin-4-ylamine dihydrochloride (CAS no: 534596-29-7) (122 mg, 0.57 mmol) in accordance with the general method 4 described in example 170 step C and was obtained as an off-white solid (210 mg, 71%); MS: m/e=520.5 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183380B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-f999c6ec996a4888a5709bb266e2d729 |
| Source note | uspto-grants-2012_05 |