HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrophenyl chloroformate → HCID 68632645, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrophenyl chloroformate | HCID 82129 | — |
| Reactant | 2-(4-Aminopiperidin-1-yl)ethan-1-ol | HCID 15733445 | — |
| Reactant | HCID 68638772 | HCID 68638772 | — |
| Product | HCID 68632645 | HCID 68632645 | — |
Reaction Steps
The title compound was prepared from rac-N2-(5-fluoro-indan-1-yl)-quinoline-2,6-diamine (Example 106) (240 mg, 0.818 mmol), 4-nitrophenyl chloroformate (165 mg, 0.818 mmol) and commercially available 4-amino-1-piperidine-ethanol (118 mg, 0.818 mmol) in accordance with the general method 4 described in example 170 step C and was obtained as an off-white solid (54 mg, 14%); MS: m/e=464.2 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183380B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-13f676493ccb4352ae9687f474e71563 |
| Source note | uspto-grants-2012_05 |