4-(N-Boc-amino)piperidine → HCID 66841966, compound

HRID 1928977Notes

Reaction equation

HRID 1928977 reaction equation
[N:1](=[CH:9][CH2:10]Cl)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]Cl.[C:12]([O:16][C:17](=[O:25])[NH:18][CH:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1)([CH3:15])([CH3:14])[CH3:13]>>[C:12]([O:16][C:17](=[O:25])[NH:18][CH:19]1[CH2:24][CH2:23][N:22]([CH2:10][CH2:9][N:1]2[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)[CH2:21][CH2:20]1)([CH3:15])([CH3:13])[CH3:14]

Participants

3

Reactant 2

HCID 7238334-(N-Boc-amino)piperidineHCID 534452782-(Hexamethyleneimino)ethyl chloride

Product 1

HCID 66841966HCID 66841966, compound

Procedure

It is synthesized analogously to ester 4 starting from 2-(hexamethylenimino)ethyl chloride (13.8 g) and ester 3 (12.4 g).

Sources & evidence

ORD record
ord-2e99704dc9274f6d87b509bf2b0dbb3e
Source dataset
uspto-grants-2012_05
Patent number
US08183366B2

Reaction notes

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