4-Isobutoxy-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amide → HCID 11166396, compound

HRID 1929044Notes

Reaction equation

HRID 1929044 reaction equation
N1(CCN2[CH2:15][CH2:14][CH:13]([NH:16][C:17]([C:19]3[NH:20][C:21]4[C:26]([CH:27]=3)=[C:25]([O:28][CH2:29][CH:30]([CH3:32])[CH3:31])[CH:24]=[CH:23][CH:22]=4)=[O:18])[CH2:12][CH2:11]2)CCCCCC1.Cl.Cl.[N:35]1([CH2:42][CH2:43][C:44]2C=CC(N)=CC=2)[CH2:41][CH2:40][CH2:39][CH2:38][CH2:37][CH2:36]1>>[N:35]1([CH2:42][CH2:43][C:44]2[CH:11]=[CH:12][C:13]([NH:16][C:17]([C:19]3[NH:20][C:21]4[C:26]([CH:27]=3)=[C:25]([O:28][CH2:29][CH:30]([CH3:31])[CH3:32])[CH:24]=[CH:23][CH:22]=4)=[O:18])=[CH:14][CH:15]=2)[CH2:41][CH2:40][CH2:39][CH2:38][CH2:37][CH2:36]1

Participants

3

Reactant 2

HCID 114420474-Isobutoxy-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amideHCID 46736401HCID 46736401, compound

Product 1

HCID 11166396HCID 11166396, compound

Procedure

This compound is synthesized analogously to Example 1 from 4-Isobutoxy-1H-indole-2-carboxylic acid 80 (preparation see Example 8) and amine 70.

Sources & evidence

ORD record
ord-3d4819b7677540199c8e6d9001424ecd
Source dataset
uspto-grants-2012_05
Patent number
US08183366B2

Reaction notes

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