HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid → 4-(Benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(1S,9aR)-1-(octahydro-quinolizin-1-yl)methyl]-piperidin-4-yl}-amide dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid | HCID 59600130 | — |
| Reactant | HCID 66841583 | HCID 66841583 | — |
| Product | 4-(Benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(1S,9aR)-1-(octahydro-quinolizin-1-yl)methyl]-piperidin-4-yl}-amide dihydrochloride | HCID 66841496 | — |
Reaction Steps
This compound is synthesized from 4-(benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid (105) (preparation see below) and amine 61 analogously to the method described in example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183366B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-3dcf912beb0d4d72842f48cdff7d3191 |
| Source note | uspto-grants-2012_05 |