HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(7-methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid → 4-(7-Methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(S)-2-((3S,4S)-4-hydroxy-3-methyl-piperidin-1-yl)-propyl]-piperidin-4-yl}-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(7-methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid | HCID 66841593 | — |
| Reactant | (3S,4S)-1-[(S)-2-(4-Amino-piperidin-1-yl)-1-methyl-ethyl]-3-methyl-piperidin-4-ol tri-hydrochloride | HCID 66841745 | — |
| Product | 4-(7-Methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(S)-2-((3S,4S)-4-hydroxy-3-methyl-piperidin-1-yl)-propyl]-piperidin-4-yl}-amide | HCID 11180669 | — |
Reaction Steps
This compound is synthesized analogously to example 1 from 4-(7-methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid, 119 (see example 80) and amine 56.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08183366B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-dacfdca78a7f4738a711f14abb097baf |
| Source note | uspto-grants-2012_05 |