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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1929126Generated: November 2, 2026

4-(6-methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid → 4-(6-Methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(1S,9aR)-1-(octahydro-quinolizin-1-yl)methyl]-piperidin-4-yl}-amide

https://huagongshe.com/reaction/1929126

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(6-methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acidHCID 66841562—
ReactantHCID 66841583HCID 66841583—
Product4-(6-Methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid {1-[(1S,9aR)-1-(octahydro-quinolizin-1-yl)methyl]-piperidin-4-yl}-amideHCID 59600253—

Reaction Steps

This compound is synthesized from 4-(6-methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid (120) (preparation see below) and amine 61 analogously to the method described in example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183366B2
Source datasetuspto-grants-2012_05
ORD IDord-970bd98ea5d947fda66266e2d122d61f
Source noteuspto-grants-2012_05