HCID 11203584, compound → HCID 11284218, compound

HRID 1929133Notes

Reaction equation

HRID 1929133 reaction equation
[N:1]1([CH2:8][CH2:9][N:10]2[CH2:15][CH2:14][CH:13]([NH:16][C:17]([C:19]3[NH:20][C:21]4[C:26]([CH:27]=3)=[C:25]([O:28][CH2:29][C:30]3[C:34]5[CH:35]=[C:36]([O:39][CH3:40])[CH:37]=[CH:38][C:33]=5[O:32][CH:31]=3)[CH:24]=[CH:23][CH:22]=4)=[O:18])[CH2:12][CH2:11]2)[CH2:7][CH2:6][CH2:5]C[CH2:3][CH2:2]1.Cl.Cl.Cl.NC1CCN(CCN2CCC([OH:59])CC2)CC1>>[OH:59][CH:5]1[CH2:6][CH2:7][N:1]([CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][CH:13]([NH:16][C:17]([C:19]3[NH:20][C:21]4[C:26]([CH:27]=3)=[C:25]([O:28][CH2:29][C:30]3[C:34]5[CH:35]=[C:36]([O:39][CH3:40])[CH:37]=[CH:38][C:33]=5[O:32][CH:31]=3)[CH:24]=[CH:23][CH:22]=4)=[O:18])[CH2:14][CH2:15]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 11203584HCID 11203584, compoundHCID 66841786HCID 66841786, compound

Product 1

HCID 11284218HCID 11284218, compound

Procedure

This compound is synthesized from 4-(5-methoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid (121, see example 92) and amine 21 analogously to the method described in example 1.

Sources & evidence

ORD record
ord-5b5ae3d7bbaa4db98bef95c647d5b54b
Source dataset
uspto-grants-2012_05
Patent number
US08183366B2

Reaction notes

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