4-(4,6-dimethoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid → HCID 66841507, compound

HRID 1929142Notes

Reaction equation

HRID 1929142 reaction equation
[CH3:1][O:2][C:3]1[C:8]2[C:9]([CH2:12][O:13][C:14]3[CH:22]=[CH:21][CH:20]=[C:19]4[C:15]=3[CH:16]=[C:17]([C:23](O)=[O:24])[NH:18]4)=[CH:10][O:11][C:7]=2[CH:6]=[C:5]([O:26][CH3:27])[CH:4]=1.[ClH:28].Cl.Cl.[C@H:31]1([CH2:41][N:42]2[CH2:47][CH2:46][CH:45]([NH2:48])[CH2:44][CH2:43]2)[C@@H:40]2[N:35]([CH2:36][CH2:37][CH2:38][CH2:39]2)[CH2:34][CH2:33][CH2:32]1>>[ClH:28].[ClH:28].[C@H:31]1([CH2:41][N:42]2[CH2:47][CH2:46][CH:45]([NH:48][C:23]([C:17]3[NH:18][C:19]4[C:15]([CH:16]=3)=[C:14]([O:13][CH2:12][C:9]3[C:8]5[C:3]([O:2][CH3:1])=[CH:4][C:5]([O:26][CH3:27])=[CH:6][C:7]=5[O:11][CH:10]=3)[CH:22]=[CH:21][CH:20]=4)=[O:24])[CH2:44][CH2:43]2)[C@@H:40]2[N:35]([CH2:36][CH2:37][CH2:38][CH2:39]2)[CH2:34][CH2:33][CH2:32]1

Participants

3

Reactant 2

HCID 668412194-(4,6-dimethoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acidHCID 66841583HCID 66841583, compound

Product 1

HCID 66841507HCID 66841507, compound

Procedure

This compound is synthesized from 4-(4,6-dimethoxy-benzofuran-3-ylmethoxy)-1H-indole-2-carboxylic acid 126 (preparation see below) and amine 61 analogously to the method described in example 1.

Sources & evidence

ORD record
ord-5f495d9440ef44f7a79034e906ea3361
Source dataset
uspto-grants-2012_05
Patent number
US08183366B2

Reaction notes

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