HCID 59600230, compound → HCID 59600249, compound

HRID 1929172Notes

Reaction equation

HRID 1929172 reaction equation
N1(CCN2CCC([NH:16][C:17]([C:19]3[NH:20][C:21]4[C:26]([CH:27]=3)=[C:25]([O:28][C:29]3[CH:34]=[CH:33][CH:32]=[C:31]([F:35])[CH:30]=3)[CH:24]=[CH:23][CH:22]=4)=[O:18])CC2)CCCCCC1.Cl.Cl.Cl.N[CH:40]1[CH2:45][CH2:44][N:43]([CH2:46][CH2:47][N:48]2[CH2:53][CH2:52][CH:51]([OH:54])[CH2:50][CH2:49]2)[CH2:42][CH2:41]1>>[OH:54][CH:51]1[CH2:52][CH2:53][N:48]([CH2:47][CH2:46][N:43]2[CH2:44][CH2:45][CH:40]([NH:16][C:17]([C:19]3[NH:20][C:21]4[C:26]([CH:27]=3)=[C:25]([O:28][C:29]3[CH:34]=[CH:33][CH:32]=[C:31]([F:35])[CH:30]=3)[CH:24]=[CH:23][CH:22]=4)=[O:18])[CH2:41][CH2:42]2)[CH2:49][CH2:50]1

Participants

3

Reactant 2

HCID 59600230HCID 59600230, compoundHCID 66841786HCID 66841786, compound

Product 1

HCID 59600249HCID 59600249, compound

Procedure

This compound is synthesized analogously to Example 1 from 4-(3-fluoro-phenoxy)-1H-indole-2-carboxylic acid 141 (see example 118) and amine 21.

Sources & evidence

ORD record
ord-0d4edc49897549fb8af21dd793828225
Source dataset
uspto-grants-2012_05
Patent number
US08183366B2

Reaction notes

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