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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1929173Generated: November 1, 2026

1-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochloride → 4-(4-Fluoro-phenoxy)-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amide

https://huagongshe.com/reaction/1929173

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-(Azepan-1-yl)ethyl)piperidin-4-amine trihydrochlorideHCID 66841393—
ReactantHCID 66841667HCID 66841667—
Product4-(4-Fluoro-phenoxy)-1H-indole-2-carboxylic acid [1-(2-azepan-1-yl-ethyl)-piperidin-4-yl]-amideHCID 59600126—

Reaction Steps

This compound is synthesized analogously to Example 1 from 4-(4-fluoro-phenoxy)-1H-indole-2-carboxylic acid 145 (preparation see below) and amine 5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183366B2
Source datasetuspto-grants-2012_05
ORD IDord-e135bd2da8c84c9b9cc2878f61fb3ba0
Source noteuspto-grants-2012_05